Repositorio institucional

Resumen: Enviromental strain of Vibrio cholera of San Luis Potosi, Mexico, do not contain functional ctxAB genes but express multiple antibiotic resistance traits

Mostrar el registro sencillo del ítem

dc.contributor.author Quezada Calvillo, R.
dc.contributor.author Villegas Tobias, E.
dc.contributor.author Recio, V.
dc.contributor.author Tovar Oviedo, J.
dc.contributor.author López Revilla, R.
dc.date.accessioned 2018-07-31T23:54:46Z
dc.date.available 2018-07-31T23:54:46Z
dc.date.issued 2004-05-26
dc.identifier.isbn 1-555-81-313-5
dc.identifier.uri https://repositorioinstitucional.uaslp.mx/xmlui/handle/i/4284
dc.description.abstract The main pathogenic factor of Vibrio cholerae O1 and O139 serotypes, causative agents of cholera, is the production of cholera toxin (CTX) encoded by the phage CTXphi. Other plasmids or integrons capable of horizontal transmission and encoding antimicrobial resistence are frequently found in O1/O139 and environmental non-O1/O139 strains. The last have are belived to constitute reservoirs for pathogenic determinants responsible of the cyclic cholera outbreaks. To identify probable reservoirs of transmissible pathogenic determinants, we analyzed the presence of ctxAB genes and the patterns of antibiotic resistance in environmental isolates of V. cholerae obtained in the state of San Luis Potosi, Mexico. Methods and results: The main sources of V. cholerae were local urban sewage waters (36.4%) and fresh waters together with derived edible products (34.4%). More than 40 different serotypes were identified, but none corresponded to the O1 or O139. Fourteen biochemical patterns were found clustered into four closely related groups. By PCR analysis two isolates obtained from marine products showed the presence of ctxAB amplification bands about 52 bp smaller than those obtained with O1 reference strains. No CTX production was detected in these two environmental strains suggesting the existence of a deletion involving the ctxA gene. A high frequence of resistance was observed against amoxicillin / clavulanic acid (73.7%), and erythromycin (30.9%); and intermediate frequence was observed against cefazolin (12.6%), cefapime (13.7%), tetracycline (8.3%) and trimethoprim / sulfamethoxazol (7.4%). Nine isolates displayed strong resistance against four to seven different antibiotics indicating the presence of chromosomal and extrachomosomal determints of antibiotic resistance. Conclusion: Enviromental V. cholerae in San Luis Potosi do not contain funtional ctxAB genes; however, transmissible elements containing antibiotic multiresistance determinants are relatively frequent. es_MX
dc.language.iso en_US es_MX
dc.publisher Facultad de Ciencias Químicas es_MX
dc.subject Vibrio cholera es_MX
dc.title Resumen: Enviromental strain of Vibrio cholera of San Luis Potosi, Mexico, do not contain functional ctxAB genes but express multiple antibiotic resistance traits es_MX
dc.type Preprint es_MX


Ficheros en el ítem

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

Buscar en el repositorio


Búsqueda avanzada

Listar

Mi cuenta